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Careful, physician-led support alongside your ALS care team

Stem cell therapy for ALS in Istanbul, Turkey

How our Istanbul program reviews your ALS stage and standard care, then offers a closely monitored, honestly explained cell therapy option.

Condition-specific editorial anatomy. Explanatory labels remain in accessible text.

Evidence position

What is known, what is investigational, and what is not demonstrated

Care foundation

Supportive, physician-supervised program

We keep riluzole, edaravone where appropriate, mutation-specific therapy, respiratory support, nutrition, and rehabilitation at the center of your plan.

Research boundary

We explain intrathecal delivery clearly

We won't let a result from one specific product or route be oversold to you as proof for a different cell source or delivery method.

Claim check

We name your exact product

Results vary between patients and stem cell therapy is not a guaranteed cure — we focus on giving you honest information and attentive care.

Direct answer

What the current evidence says

Our Istanbul physicians evaluate your ALS stage, respiratory status, and current care plan before discussing any cell therapy option. We are candid about what the evidence shows and does not show, and we build every plan to run alongside — never instead of — the multidisciplinary ALS care that keeps you strongest for longest. Request your free medical evaluation and we'll talk through what a supervised program can and cannot offer you.

Clinical map

Start with the diagnosis, stage, and treatment context

We present any cell-based option as investigational and keep it clearly separate from — and coordinated with — your multidisciplinary ALS care.

Established care comes first

  • ALS specialist coordination: We work alongside your neurology, respiratory, nutrition, speech, and mobility team rather than replacing it.
  • Disease-modifying treatment: We review riluzole, edaravone, and genotype-specific options with you and keep them active throughout your program.
  • Function preservation: Noninvasive ventilation, cough support, feeding planning, and communication tools stay part of your care while in Istanbul.
  1. 01

    Phenotype and tempo

    We factor in limb onset, bulbar onset, respiratory involvement, and your rate of change when shaping a program and timeline.

  2. 02

    Diagnostic confidence

    We review your EMG, imaging, labs, and genetic testing so your plan reflects your exact diagnosis.

  3. 03

    Respiratory and nutrition needs

    We coordinate around your breathing capacity, swallowing, weight, and aspiration risk so travel and care stay safe.

Evidence ledger

Read the actual study, including the result that did not change

Each row keeps product identity, route, endpoint, and limitation together so one trial cannot become a generic treatment claim.

  1. 01

    NurOwn phase 3 trial

    Open source
    Product
    Autologous bone marrow MSCs induced to secrete neurotrophic factors
    Route
    Three intrathecal administrations
    Design
    Randomized, double-blind, placebo-controlled phase 3 study
    Finding
    The overall population did not show a statistically significant benefit on the primary responder endpoint or the key ALSFRS-R secondary endpoint.
    Limitation
    Post hoc subgroup signals are hypothesis-generating and do not establish benefit or support extrapolation to another product.

Product and route

A mechanism is not a clinical outcome

  1. 01

    We explain intrathecal delivery clearly

    Lumbar puncture carries its own risks and we walk you through them before any decision, rather than implying it reconnects motor neurons.

    BoundaryEvidence applies only to the studied product, population, dose, route, comparator, and endpoint.

  2. 02

    We name your exact product

    Autologous MSC-NTF, unmodified MSCs, cord tissue products, and exosomes are different interventions — your evaluation tells you precisely which one is proposed and why.

    BoundaryEvidence applies only to the studied product, population, dose, route, comparator, and endpoint.

Man seated beside a transparent anatomical figure showing the brain, spinal cord, peripheral nerves, and a close-up of a neuromuscular junction

Outcomes before travel

Decide what meaningful change would look like

A baseline and a time point matter more than an isolated testimonial. These measures should be chosen before any intervention.

  1. 01

    ALSFRS-R trajectory

  2. 02

    Slow vital capacity or FVC

  3. 03

    Weight and swallowing safety

  4. 04

    Time to ventilation, feeding support, or hospitalization

  5. 05

    Any treatment-related side effects

Specialist review

What a complete Istanbul review needs

How our Istanbul program reviews your ALS stage and standard care, then offers a closely monitored, honestly explained cell therapy option.

Records and baseline

  • Neurologist-confirmed diagnosis and onset pattern
  • Serial ALSFRS-R and respiratory results
  • EMG, imaging, and genetic results
  • Current medicines, swallowing, nutrition, mobility, and communication supports
  • The exact product, dose, route, and physician oversight we recommend for you

Safety and planning checks

  • We never ask you to interrupt proven medicines, respiratory care, nutrition, or multidisciplinary follow-up to travel.
  • Your Istanbul review includes fitness for lumbar puncture, infection and anticoagulation screening, and a written safety plan.
  • We'll tell you plainly if respiratory, bulbar, or medical instability makes travel unsafe right now.

Transparent planning

Build the medical plan before the package

A quote should follow record review, product disclosure, route rationale, and a written follow-up plan. This page does not invent a universal price.

  • We never ask you to interrupt proven medicines, respiratory care, nutrition, or multidisciplinary follow-up to travel.
  • Your Istanbul review includes fitness for lumbar puncture, infection and anticoagulation screening, and a written safety plan.
  • We'll tell you plainly if respiratory, bulbar, or medical instability makes travel unsafe right now.
Read the cost and planning guide

Questions the plan must answer

  1. 01

    We explain intrathecal delivery clearly: Lumbar puncture carries its own risks and we walk you through them before any decision, rather than implying it reconnects motor neurons.

  2. 02

    We name your exact product: Autologous MSC-NTF, unmodified MSCs, cord tissue products, and exosomes are different interventions — your evaluation tells you precisely which one is proposed and why.

FAQ

Questions patients ask before an Istanbul review

No product has been shown to reverse ALS, and we won't tell you otherwise. The best known phase 3 intrathecal MSC-NTF study missed its prespecified primary and key secondary endpoints overall. We focus on a well-run, honestly explained supportive program.

Request Medical Evaluation

Begin a personalized treatment conversation with our medical team.

Share your case in confidence. Our international coordinators review every enquiry and respond within 24 hours, in your language.