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Istanbul Stem Cells logo

One diagnosis, many organ patterns

Stem cell therapy for lupus in Istanbul, Turkey

An organ-specific program combining MSC-based immune modulation with your existing lupus care, physician monitoring, and transparent Istanbul pricing.

Conceptual biological visualization

Evidence status

What the evidence can support now

Established care

Organ and activity-specific treatment stays central

Hydroxychloroquine, glucocorticoids, immunosuppressants, and approved biologics remain selected around your disease activity and organ involvement.

What we add

Cell-based immune modulation

For severe or refractory disease, we coordinate access to MSC studies, transplant programs, and CAR-T research where appropriate.

What we won't promise

A simple, risk-free immune reset

We won't promise a generic infusion that restores the immune system or removes the need for medication. We walk you through the real risks and uncertainty.

A direct answer

The short answer

We offer cell-based immune-modulation protocols for carefully selected, treatment-refractory systemic lupus erythematosus. MSC infusion, autologous hematopoietic stem-cell transplantation, and CAR-T are fundamentally different options, and none replaces your standard lupus or lupus-nephritis care. Results vary between patients and stem cell therapy is not a guaranteed cure.

Start with the phenotype

Your lupus phenotype shapes the plan

Skin and joint disease, nephritis, CNS involvement, blood abnormalities, and cardiopulmonary disease each carry a different risk profile and protocol.

Lupus care never pauses for a package

We keep your specialist team's plan for controlling activity and preventing organ damage running throughout.

  • Antimalarial therapy for most suitable patients
  • Organ and activity-specific immunosuppressive treatment
  • Approved biologics for selected disease patterns
  • Kidney, blood, cardiovascular, bone, infection, and pregnancy monitoring
  • Shared decisions across rheumatology, nephrology, neurology, hematology, or cardiology as needed
  1. 01

    Lupus nephritis

    Proteinuria, kidney function, biopsy class, and response to standard therapy drive urgency and safety.

  2. 02

    Neuropsychiatric lupus

    Seizure, stroke, psychosis, neuropathy, and other presentations require specialist evaluation.

  3. 03

    Hematologic disease

    Cytopenias, clotting, antiphospholipid syndrome, and bleeding risk affect candidacy.

  4. 04

    Cardiopulmonary disease

    Pericarditis, myocarditis, pulmonary hypertension, and lung disease can affect travel safety.

Product and route matter

Three options, kept clearly separate

We name the product and clinical setting so you always know exactly what you're being offered.

  1. 01

    Mesenchymal stromal cells

    Usually allogeneic IV products studied for paracrine immune modulation.

    Evidence boundaryEarly-phase evidence; we're transparent about current limits.

  2. 02

    Autologous HSCT

    Conditioning chemotherapy suppresses the immune system before blood-forming stem cells are returned.

    Evidence boundaryCarries infection, infertility, organ toxicity, and treatment-related mortality risk that we review with you in full.

  3. 03

    CAR-T cell therapy

    Engineered immune cells target B-cell biology in highly specialized research settings.

    Evidence boundaryNot a stem-cell infusion — a distinct, intensive investigational treatment.

  4. 04

    Exosome products

    Acellular vesicle products are marketed commercially elsewhere.

    Evidence boundaryNo FDA-approved exosome product exists for lupus, and we don't overstate what these can do.

Indexed evidence ledger

The evidence, honestly presented

A six-person safety study and a registered trial show research activity, and we present them as exactly that — not proof of routine benefit.

  1. 01

    US phase I MiSLE study

    Open study
    Product
    Single IV dose of allogeneic umbilical-cord MSCs
    Study design
    Early safety study in six women with refractory lupus
    Finding
    Provided feasibility and safety observations for further study.
    Limitation
    Extremely small and uncontrolled; not designed to establish efficacy.
  2. 02

    MiSLE phase II

    Open study
    Product
    MSC strategy in moderate to severe lupus
    Study design
    Randomized US clinical trial record
    Finding
    Completed in 2026 with no posted results at the time of review.
    Limitation
    Registration and completion don't establish benefit until results are reported.
  3. 03

    French phase I dose escalation

    Open study
    Product
    Allogeneic MSC infusion
    Study design
    Single-center open-label severe refractory SLE study
    Finding
    Focused on feasibility and safety across doses.
    Limitation
    Small early-phase design; not yet suited to routine clinical claims.
Cinematic immune and microvascular landscape showing antibody-like forms, vessel lining, and subtle kidney, skin, and joint structures.

Measure what changes

We track your disease activity and organs

Energy and sleep matter, but we always pair them with a validated lupus activity and organ-safety plan.

  1. 01

    Disease activity

    SLEDAI, BILAG, flare rate, steroid exposure, and physician global assessment.

  2. 02

    Immune markers

    Complement, anti-dsDNA, CBC, and other markers interpreted in clinical context.

  3. 03

    Kidney outcomes

    Creatinine, eGFR, urinalysis, proteinuria, sediment, and biopsy context when relevant.

  4. 04

    Patient function

    Fatigue, pain, participation, sleep, and quality of life with validated measures.

Rheumatologist and nephrologist reviewing organ-specific lupus records with an adult patient in an Istanbul consultation room.

Clinical review before travel

A multidisciplinary Istanbul evaluation

Your review identifies active organs, current disease control, treatment history, infection risk, and travel stability before any protocol is proposed.

Records to send

  • Rheumatology summary, diagnosis, activity, and organ history
  • Medication and biologic timeline with response and adverse effects
  • CBC, creatinine, eGFR, urinalysis, proteinuria, complements, and anti-dsDNA
  • Kidney biopsy, echocardiogram, lung, neurologic, or hematology records when relevant
  • Infection, vaccination, pregnancy, clotting, and malignancy history

Reasons to pause

  • Active infection, fever, or inadequately evaluated cytopenia
  • Unstable nephritis, CNS, cardiac, pulmonary, or thrombotic disease
  • Pregnancy or another trial-specific exclusion requiring specialist guidance
  • Any proposal to stop lupus medication or call an infusion a risk-free immune reset

Transparent planning

Lupus stem cell therapy cost in Istanbul, Turkey

Your quote names clearly whether it covers an outpatient MSC protocol, a hospital-based procedure, or another intensive intervention, since these carry very different prices and risk profiles.

For context, our general 2026 MSC planning range is $7,000-$18,000. This does not cover HSCT or CAR-T; your quote is itemized to your exact protocol.
  • Organ-specific rheumatology and subspecialty review
  • Exact intervention, source, dose, route, and release testing
  • Hospital, laboratory, infection, and observation requirements
  • Medication coordination and longitudinal organ monitoring
Read the full cost guide

Questions patients ask us

  1. 01

    How much does lupus stem cell therapy cost in Turkey?

  2. 02

    Is this MSC infusion, autologous HSCT, CAR-T, or an acellular product?

  3. 03

    How many days will I need in Istanbul for evaluation and treatment?

  4. 04

    How will activity, steroid exposure, kidney function, and flares be tracked with my specialists?

FAQ

Questions about lupus

No, and we won't claim otherwise. Our program focuses on selected refractory disease as an addition to, never a replacement for, proven treatment. Results vary between patients and stem cell therapy is not a guaranteed cure.

Request Medical Evaluation

Begin a personalized treatment conversation with our medical team.

Share your case in confidence. Our international coordinators review every enquiry and respond within 24 hours, in your language.